Lung Cancer A Common Malignant Disease - 794 Words

Introduction Lung cancer is a very common malignant disease around the world, which is mainly caused by long-term exposure to tobacco smoke (85% of all cases). [1] It is reported by WHO that, globally in 2012, 1.8 million people suffered from lung cancer, and 1.6 million patients died of lung cancer. [2] In cancer-related death all around the world, lung cancer ranks the top in men and second in women, only after breast cancer. [3] Statistically, 17.4% of lung cancer patients in the United States only have five-year survival after the diagnosis, and the average survival rate is even worse in the developing countries. [4] There are three main types of lung cancer, knowing as non-small cell lung cancer, small cell lung cancer, and lung carcinoid tumor. Among them, non-small cell lung cancer (NSCLC) is the most common one, which covers about 85% to 90% of lung cancer cases. [5] There are several common therapies for NSCLC, including surgery, chemotherapy, and radiation therapy. And the choice of therapy or therapies is based on lung cancer staging, which represents the degree of metastasis of tumor cells. [6] Usually, the TNM classification is used to evaluate NSCLC staging. This classification is based on the size of the primary tumor, whether lymph node is involved, and how about the degree of metastasis. [7] Generally, for early-stage NSCLC, the combination of surgery, chemotherapy, and radiation therapy is the most common and efficient treatment. However, for advancedShow MoreRelatedCancer : The Leading Cancer Killer1159 Words   |  5 PagesEveryone in the world today has been impacted by cancer i n some way. Lung cancer is the leading cancer killer in both men and women in the United States. In 1987, it surpassed breast cancer to become the leading cause of cancer deaths in women. Lung cancer causes more deaths than the next three most common cancers combined (colon, breast and pancreatic). 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